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Cell Tissue Gene DNA Mitosis Meiosis


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Transcription

Transcription :

*Process where the information in DNA is transcribed to a RNA molecule (mRNA)

*Occur in the nucleus

*Single strand of DNA act as as a template

*Only part of DNA will be copied

*Direction : 5’ 3’

*Catalaysed by RNA polymerase

Initiation

*RNA polymerase binds to DNA at a specific sequence of nucleotides called the promoter

*The promoter contains an initiation site where transcription of the gene begins

*RNA polymerase than unwinds DNA at thebeginning of the gene

Elongation

*Only one of the unwound DNA strands acts as a template for the RNA synthesis

*RNA polymerase can only add nucleotids to the 3' end of the strand so like DNA, RNA must be synthesized in the 5' to 3' direction

*Free ribonucleotides from the cytoplasm are paired up with their complementary base on the exposed DNA template

*RNA polymerase joins the ribonucletides to form mRNA strand

*The DNA that has been transcribed, re-winds to form a double helix

Termination

*RNA polymerase continues to elongate until it reaches the terminator, a specific sequence of nucleotides that signals the end of transcription

*Transcription stops and mRNA polymerase and the new mRNA transcript are released from DNA. DNA double helix reforms

Animation : Transcription Process


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